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1.
Appl Opt ; 56(10): 2783-2786, 2017 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-28375241

RESUMO

An overall quantum conversion efficiency of 7.8% is achieved by intracavity mixing the signal and idler of a 1.064 µm pumped Rb:PPKTP optical parametric oscillator in BaGa4Se7. In this way, a pulse energy of ∼0.71 mJ is generated at ∼7 µm for a repetition rate of 100 Hz. Tuning of the mid-IR radiation is demonstrated by heating of the Rb:PPKTP crystal.

2.
J Biomed Opt ; 22(1): 17002, 2017 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-28122081

RESUMO

The infrared laser photoacoustic spectroscopy (LPAS) and the pattern-recognition-based approach for noninvasive express diagnostics of pulmonary diseases on the basis of absorption spectra analysis of the patient's exhaled air are presented. The study involved lung cancer patients ( N = 9 ), patients with chronic obstructive pulmonary disease ( N = 12 ), and a control group of healthy, nonsmoking volunteers ( N = 11 ). The analysis of the measured absorption spectra was based at first on reduction of the dimension of the feature space using principal component analysis; thereafter, the dichotomous classification was carried out using the support vector machine. The gas chromatography­mass spectrometry method (GC­MS) was used as the reference. The estimated mean value of the sensitivity of exhaled air sample analysis by the LPAS in dichotomous classification was not less than 90% and specificity was not less than 69%; the analogous results of analysis by GC­MS were 68% and 60%, respectively. Also, the approach to differential diagnostics based on the set of SVM classifiers usage is presented.


Assuntos
Testes Respiratórios/métodos , Neoplasias Pulmonares/diagnóstico , Técnicas Fotoacústicas/métodos , Doença Pulmonar Obstrutiva Crônica/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Testes Respiratórios/instrumentação , Estudos de Casos e Controles , Expiração , Cromatografia Gasosa-Espectrometria de Massas , Humanos , Pessoa de Meia-Idade , Reconhecimento Automatizado de Padrão , Técnicas Fotoacústicas/instrumentação , Análise de Componente Principal , Sensibilidade e Especificidade , Máquina de Vetores de Suporte
3.
Opt Lett ; 41(15): 3667-70, 2016 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-27472645

RESUMO

A BaGa4Se7 nanosecond optical parametric oscillator (OPO) shows extremely wide idler tunability in the mid-IR (2.7-17 µm) under 1.064 µm pumping. The ∼10 ns pulses at ∼7.2 µm have an energy of 3.7 mJ at 10 Hz. The pump-to-idler conversion efficiency for this wavelength reaches 5.9% with a slope of 6.5% corresponding to a quantum conversion efficiency or pump depletion of 40%.

4.
Opt Lett ; 41(12): 2791-4, 2016 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-27304290

RESUMO

A 1.064 µm pumped Rb:PPKTP optical parametric oscillator (OPO) generates mid-IR radiation by intracavity mixing the resonant signal and idler waves in AgGaSe2. The ∼6 ns pulses at ∼7 µm have an energy of 670 µJ at 100 Hz, equivalent to an average power of 67 mW. The overall quantum conversion efficiency from 1.064 µm amounts to 8%, and the power conversion efficiency is 1.2%.

5.
Opt Express ; 23(26): 33460-5, 2015 Dec 28.
Artigo em Inglês | MEDLINE | ID: mdl-26832010

RESUMO

A AgGaSe2 nonlinear crystal placed in a coupled cavity is intracavity pumped by the ~1.85-µm signal pulses of a 1.064-µm pumped Rb:PPKTP doubly-resonant optical parametric oscillator (OPO) operating at a repetition rate of 100 Hz. Using two samples cut for type-I and II phase-matching, the overall idler tunability of the singly-resonant AgGeSe2 OPO covers an unprecedented spectral range from 5.8 to ~18 µm in the mid-IR.

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